Wolverhampton Wanderers stun Liverpool 2-1 with a 94th-minute winner to revive survival hopes and dent the Reds' top-five push, while Everton and Sunderland claim crucial Premier League victories.
Liverpool substitute Curtis Jones and Everton midfielder Abdoulaye Doucoure were also shown red cards after the game, and the final whistle sparked a scuffle between both sets of players.
Everton's Ashley Young came on as a second-half substitute but his 18-year-old son Tyler remained on the Peterborough bench.
A round-up of Saturday's action in the Premier League.
'As a centre-forward, you can make a lot of runs sometimes and not get the ball. You need a lot of things to come together for it to be a goal.'
Footage emerged on social media of Ronaldo appearing to swipe his hand towards the ground as he walked off the pitch and headed for the tunnel at Goodison Park. Eyewitnesses said the 37-year-old had knocked a fan's phone out of their hand and it smashed to the ground.
Liverpool will resume their quest for a first top-flight title in 30 years against Everton on June 21 but the venue for the behind-closed-doors fixture was not confirmed when the league released its revised fixtures for the season's restart.
Liverpool regained their place at the top of the English Premier League with a 2-0 win at Cardiff City on Sunday that restored their two-point lead over Manchester City
Everton battled back from two goals down to draw 2-2 at home to Liverpool in the first Merseyside derby of the season at Goodison Park on Sunday.
Liverpool's new owners watched their team slump to a comprehensive 2-0 defeat at Merseyside rivals Everton which sent them second bottom of the Premier League on Sunday.
Liverpool captain Steven Gerrard scored the first hat-trick in a Merseyside league derby since 1982 as his side enjoyed an emphatic 3-0 victory over Everton in the Premier League at Anfield on Tuesday.
Liverpool beat Everton 2-1 in a dramatic EPL Merseyside derby on Saturday at Goodison Park.
Chelsea and Liverpool maintained their unbeaten starts to the season and kept the pressure on early pace-setters Arsenal when they both chalked up 2-0 away wins in the Premier League on Saturday.
Images from Saturday's action in the English Premier League.
Steven Gerrard scored two penalties as Liverpool went back to the top of the Premier League with a 2-1 win at West Ham United to complete a Merseyside win-double over London clubs on Sunday.
Liverpool's new American era began in failure on Sunday in front of their latest owners with a 2-0 loss to Merseyside rivals Everton which sent them second from bottom of the Premier League.
Vitaliy Mykolenko's 39th-minute own goal had put Luton ahead before Jack Harrison cheered the Everton faithful with an equaliser in the 55th minute, hammering in a low shot that Luton keeper Tim Krul allowed to let slip through his hands.
Manchester City and Everton players took to the field wearing Ukrainian flags before their Premier League game on Saturday while there were anti-war messages at stadiums elsewhere following Russia's invasion of Ukraine.
Manchester United closed in on the Premier League's pole position after a 2-1 home win over Aston Villa on Friday put them level on points and games played with champions and leaders Liverpool.
A round-up of Sunday's action in the Premier League.
Images from the English Premier League matches played on Sunday night.
It promises to be a tense and thrilling finale to the season but Liverpool, who have frittered away a seven-point lead, will need to regain their momentum quickly if they are to push for their first league title since 1990.
Saints' keeper Angus Gunn saved Theo Walcott's penalty and defender Cedric slotted his effort past Maarten Stekelenburg to put the visitors into the last-16 where they will play away at Leicester City.
Liverpool may have to wait a little longer for their Premier League title celebrations after they were held to a 0-0 draw at Everton in the behind closed-doors Merseyside derby on Sunday.
Premier League heavyweights Liverpool and Manchester United were caught by late sucker punches in two games that finished far more dramatically than they began on Sunday.
Everton have filed an appeal against their 10-point deduction by the Premier League, the club said on Friday.
A round-up of Saturday's action in the Premier League.
Liverpool climbed to the top of the Premier League table with a 2-1 victory over struggling Wolverhampton Wanderers on Saturday.
Anthony Martial introduced himself to Manchester United fans with a superb goal to complete a 3-1 win over bitter rivals Liverpool and cap a much-improved performance from Louis van Gaal's side on Saturday.
Everton sacked manager Rafa Benitez on Sunday following their 2-1 defeat at Norwich City which left the Merseyside club six points above the Premier League relegation zone in 15th place.
Young becomes oldest Everton scorer in rout of Wolves
Images from Saturday's action in the Premier League.
A round-up of Saturday's action in the Premier League.
Arsenal sent Liverpool crashing out of the FA Cup, avenging last weekend's rout at Anfield, when they beat Brendan Rodgers's high-flyers 2-1 in a full-bloodied fifth round tie at the Emirates Stadium on Sunday.
The Premier League's bottom two clubs met at Goodison Park and there was more woe for Everton as they bowed out on penalties to Southampton after a 1-1 draw.
Images from Saturday's action in the English Premier League.
Everton beat Portsmouth 3-1 at Goodison Park to move back into fourth place in the English Premier League.
"When he has the ball at his feet, he can make things happen for himself and he can make things happen for other players. He is a very special player."
Images from the English Premier League matches played on Wednesday.
IMAGES from Premier League matches played on Sunday.
